Quantification of albendazole by ultraviolet spectrophotometer in tablet
[ps2id id=’background’ target=”/] BACKGROUND Albendazole is used as antihelminthic drug, that is used against parasitic worm infestations. Few of the symptoms listed are hydatid disease, neurocysticercosis, giardiasis, filariasis. The mode…
Synthesis of 9, 10-dihydroanthracene-9, 10-endo-α, β-succinic anhydride from anthracene
[ps2id id=’background’ target=”/] BACKGROUND Principle: The reaction of conjugated dienes with the ethylenic or acetylenic compound to form a six member cyclic product commonly known as “adduct” and reaction is…
Synthesis of 3-phenyl propionic acid (hydrocinnamic acid) from diethylmalonate.
[ps2id id=’background’ target=”/] BACKGROUND Principle: Here 3-phenylpropionic acid is produced finally from benzylated malonic acid due to decarboxylation on heating. First freshly prepared sodium ethoxide reacts with diethyl malonate giving…
Study the anti-convulsant/antiepileptic activity of drug against chemical induced convulsions
[ps2id id=’background’ target=”/] BACKGROUND Seizures are one of the complications of drug toxicity commonly antihistaminics and antidepressants due to insufficient inhibitory action (e.g., GABA) or extreme excitation (e.g., glutamate).1 Pentylenetetrazol…
Study the anti-convulsant/antiepileptic activity of drug against maximum electroconvulsive seizure (MES)
[ps2id id=’background’ target=”/] BACKGROUND Convulsion in animals (rats/mice) can be induced by high voltage electric shock near brain. This experiment is a standard experiment for anti-convulsant activity screening and predicts…