Synthesis of hippuric acid (benzoyl glycine) from glycine
[ps2id id=’background’ target=”/] BACKGROUND Principle: Benzoyl glycine is an amide and amide contains a molecule of an organic acid linked to a molecule of an amine. A water molecule must…
Synthesis of fluorescein from resorcinol and phthalic anhydride
[ps2id id=’background’ target=”/] BACKGROUND Principle: Here a modified Friedel-crafts acylation reaction is occurring. This reaction is a series of electrophilic aromatic substitutions, with hydroxyl leaving groups picking up protons by…
Synthesis of chalcone from benzaldehyde and acetophenone
[ps2id id=’background’ target=”/] BACKGROUND Principle: Aromatic aldehyde condense with aliphatic or mixed aryl alkyl ketone in presence of aqueous alkali to form α, β-unsaturated ketone, which is well known as…
Synthesis of benzotriazole
[ps2id id=’background’ target=”/] BACKGROUND Principle: Benzotriazole can be prepared by treating o-phenylenediamine with nitrous acid (liberated during the reaction between sodium nitrite and acetic acid) to form mono-diazonium salt that…
Synthesis of benzamide from benzaldehyde
[ps2id id=’background’ target=”/] BACKGROUND Aim: To prepare benzamide from benzaldehyde Principle: The first step involves the formation of the anion which transfers a hydride ion on to a carbonyl carbon…
Synthesis of barbituric acid from urea and dimethyl malonate.
[ps2id id=’background’ target=”/] BACKGROUND Principle: The synthesis of barbituric acid is effected by condensation of diethyl malonate with urea in the presence of sodium ethoxide which may be prepared by…
