Labmonk quiz, NET Life Science,
#1. With which protein of Yersinia would integrin proteins of mammalian cells interact for internalization?
#2. Two E. coli cultures A and B are taken. Culture A was earlier grown in the presence of optimum concentration of gratuitous inducer IPTG. Both the cultures are now used to inoculate fresh medium containing sub-optimal concentration of gratuitous inducer. It was observed that culture B was unable to utilize lactose, whereas culture A did so efficiently. The reason behind this is
#3. TH2 response is generated and maintained mainly by which of the following pair of cytokines?
#4.
Presence of circular mRNAs for a specific protein in a eukaryotic cell reflects a rapid rate of synthesis of that protein. Following mechanisms are suggested:
P. eIF-4G and PABP promote this process through 5’-3’ interaction of mRNA.
Q. ribosomes are less active in recognizing circular mRNA.
R. PABP and eIF-4A promote this process.
S. ribosomes can reinitiate translation without being disassembled.
Which of the following is correct?
#5. It has been observed that in 5-10% of the eukaryotic mRNAs with multiple AUGs, the first AUG is not the initiation site. In such cases, the ribosome skips over one or more AUGs before encountering the favourable one and initiating translation. This is postulated to be due to the presence of the following consensus sequence(s):
P. CCA CC AUG G
Q. CCG CC AUG G
R. CCG CC AUG C
S. AAC GG AUG A
Which of the following sequence sets related to the above postulations is correct?
#6.
Genetic studies demonstrated that TBP mutant cell extracts are deficient in transcription of genes from all three promoters viz. class I, II and III. Following statements describe characteristic features of TBP.
P. TBP is considered as a universal basal transcription factor.
Q. TBP is not required for transcription of archaeal genes.
R. TBP is involved in recognizing TATA box.
S. TBP operates at all promoters regardless of their TATA content.
Which of the following combination is not correct?
#7. During generation of an action potential, depolarization is due to
#8. Which of the following molecules is involved in Ca2+-dependent cell-cell adhesion?
#9.
siRNAs and miRNAs are used for achieving gene silencing. Although, major steps are similar there are distinct differences in the key players of the two processing pathways. Following statements are related to some characteristic features of gene silencing.
P. Both siRNAs and miRNAs are processed by cytoplasmic endonuclease Dicer.
Q. Drosha is needed for processing miRNAs and precursor siRNAs.
R. Both siRNAs and miRNAs show association with Argonaute protein.
S. Both the processing pathways involve RISC complex.
Which of the following combinations is not correct?
#10. G protein-linked receptors are transmembrane proteins of
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