Quiz 24-August-2023

#1. Following are endogenous carriers use for targeted drug delivery except: -

Microparticulate

Lipoprotein

Serum Albumin

Erythrocyte

#2. Which test is done for USP Type-I glass containers for injections?

Powdered glass followed by water attack test

Water attack followed powdered glass test

Water attack test

Powdered glass test

#3. As per USP, test limit for treated soda lime glass with container size of 200 ml is:-

0.20ml of 0.02N Acid

0.70ml of 0.2N Acid

0.70ml of 0.02N Acid

1.0ml of 0.2N Acid

#4. Vials and bottles are regularly not subjected to following test:-

Sterility test

Leaker (chamber) test

Pyrogen test

Clarity test

#5. Which of the following formula is used to determine shelf life as per first order reaction?

t1/2 0.693/k

t90 0.693/k

t90 0.104/k

t1/2 0.105/k

#6. In plasma, phenobarbital is present as ionized and unionized forms in equal amount because: -

It is weakly basic drug

pKa of the phenobarbital is 7.4

It is weakly acidic drug

pH of plasma is 6.8

#7. What is the effective ratio of methyl paraben and propyl paraben for anti-microbial activity?

1:1

5:1

10:1

2.5:1

#8. What are the specific surface per unit volume Sv of spherical particles with density of 3 gm/cm3 and volume surface diameter, dvs of 2.57μm?

7.78 x 103 cm2/cm3

1.55 x 103 cm2/cm3

2.33 x 103 cm2/cm3

1.00 x 103 cm2/cm3

#9. The friability issue of the tablet can be solved by different ways except: -

Adjusting the lower punch pressure of tablet machine

Increasing the moisture content of granules

Addition of more tablet binder to granules

Increasing the upper punch pressure of tablet machine

#10. A material which is insoluble and inert and used in matrix tablet formulation is: -

Polyethylene glycol

Stearyl alcohol

Polyethylene

Triglycerides

Finish

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