BACKGROUND
Critical Micelle Concentration (CMC)
Aim of the experiment: To determine CMC of a surfactant using stagmometer.
REQUIREMENTS
Chemicals:
- SLS,
- Distilled water
Apparatus:
- Stagmometer,
- Analytical balance.
Principle:
Critical micelle concentration is defined as the concentration of surfactant at which the mycein is stands to forming.
PROCEDURE
250 ml of stocks solution of surfactant SLS was prepared using distilled water having concentration of 1mg per solution from the stocks solution strength of surfactant were prepared using distilled water i.e 5,10,15,20,25,30,35,40 mg /ppm. Now the surface tension of each of the strength solution was determined.1-3
A graph was plotted taking concentration on X- axis and surface tension on Y-axis.
Tabulation:
| Concentration of reactant | 1 | 2 | 3 | Mean | Density(ρ) | Surface tension(ϒ) |
| 5 | ||||||
| 10 | ||||||
| 15 | ||||||
| 20 | ||||||
| 25 | ||||||
| 30 | ||||||
| 35 | ||||||
| 40 | ||||||
| 45 | ||||||
| 50 |
CONCLUSION
Concentration of the given surfactant was found to be _ by using in the graphical method.
REFERENCES
- More HN, Hajare AA. Practical Physical Pharmacy. Career Publications. 2010: 156-157.
- Gaud RS, Gupta GD. Practical Physical Pharmacy. CBS Publisher and Distributors. 2009: 75-76.
- Mohanta GP. Physical Pharmacy Practical Text, Pharma Book Syndicate. 2006: 39-40.
Also read:
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- Determination of viscosity of liquid using Ostwald viscometer
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- Protein denaturation by egg albumin method (in vitro)
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- Analgesic activity study of drugs by tail-flick method
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