Determination of Glident Efficiency

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BACKGROUND

Glident Efficiency

Aim: To study the effect of glident on angle of repose and to determine glident efficiency from flow rate.

Angle of repose is defined as the maximum angle possible between the surface area of the pile of powder and horizontal plane. The angle of repose is given by

(o) = tan-1 h/r

Where, h = height of pile

r = radius of the base of the pile

Bulk density is defined as the ratio of weight of powder to the bulk volume is the volume occupied by certain weight of powder when gently poured into the measuring cylinder.

Bulk density = weight / bulk volume

Tapped density is the ratio of weight of powder to the tapped volume and Tapped volume is the volume occupied by certain weight of powder after standard no. of tapping.

Tapped density = weight / tapped volume

Carr’s index may be defined as

Carr’s index = (Tapped density – bulk density / tapped density)× 100

Hausner’s ratio is the no. i.e co-related to flowability of the powder.

Hausner’s ratio = Tapped density / bulk density

Glidantefficeancy=Time of flow with glident/Time of flow with outglident.1-3

REQUIREMENTS

Chemical:      

  • Lactose.Talc,
  • Starch,
  • Mangesiumsterate.

Apparatus:     

  • Funnel,
  • Burette stand,
  • Stop watch.

PROCEDURE

Take the sample mixture containing Lactose and Glident. Then it was poured in to the funnel keeping the tip of the funnel closed. A white paper was placed below the funnel on a solid surface.

The distance between the tip and the solid surface kept nearly 5 cm. Now the tip of the funnel is opened so that a tip of the powder formed. Time of flow, height, radious of the hip was measured. By using the formula angle of repose and glident efficiency can be calculated.

tanθ =h/r

θ=tan-1h/r

Glidant efficeancy=Time of flow with glident/Time of flow with outglident.

FormulaLactoseTalcStarchMagnesiumsterateAngle ofreposeTime offlowGlident efficiency
F110gm
F210gm1
F310gm2
F410gm3
F510gm1
F610gm2
F710gm3
F810gm1
F910gm2
F1010gm3

CONCLUSION

From the above experiment we concluded that glident _____________ at concentration __________has maximum glident efficiency.

REFERENCES

  1. More HN, Hajare AA. Practical Physical Pharmacy. Career Publications. 2010: 123-124.
  2. Gaud RS, Gupta GD. Practical Physical Pharmacy. CBS Publisher and Distributors. 2009: 45-46.
  3. Mohanta GP. Physical Pharmacy Practical Text, Pharma Book Syndicate. 2006: 52-53.

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