Top 50 Research Topics in Biotechnology

Nanotechnology

Here comes another interesting part of biotechnology, that can be utilized for recognizing some powerful tools for addressing major health problems. Let’s check the list of biotechnology topics.

Topics

1. Evaluating cancer-specific peptides for applications in the diagnosis of cancer.
2. The development of quantum dot-based detection system for the diagnosis of breast cancer.
3. Fabrication of target specific Nano-constructs for in vivo imaging and treatment of cancer.
4. Evaluating novel quinone compounds as anti-cancer agents.
5. Targeted delivery of embelin to cancer cells.
6. Biochemical investigation of the anti-cancer activity of Tulbaghia violacea extracts.
7. Screening the anti-cancer activity of novel organo-metallic compounds.
8. Development of nanotechnology-based therapeutic approaches to treat HIV.

Some of the Current Research Topics in Biotechnology:

1. The scheduled simple production method of pseudo-pregnant female mice for embryo transfer using the luteinizing hormone-releasing hormone agonist.
2. Functionalizing DNA origami to investigate and interact with biological systems
3. The potential impact of nanomedicine on COVID-19-induced thrombosis
4. Challenges and developments in universal vaccine design against SARS-CoV-2 variants
5. Empowering gene delivery with protein engineering platforms
6. Joint structural annotation of small molecules using liquid chromatography retention order and tandem mass spectrometry date
7. Active eosinophils regulate host defence and immune responses in colitis
8. Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA
9. Bead-jet printing enabled sparse mesenchymal stem cell patterning augments skeletal muscle and hair follicle regeneration
10. An RNA-targeting CRISPR–Cas13d system alleviates disease-related phenotypes in Huntington’s disease models
11. Engineering antiviral immune-like systems for autonomous virus detection and inhibition in mice
12. A plant-derived natural photosynthetic system for improving cell anabolism
13. Selective targeting of visceral adiposity by polycation nanomedicine
14. Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases
15. Analysis of clinically relevant variants from ancestrally diverse Asian genomes
16. Self-cleaving guide RNAs enable pharmacological selection of precise gene editing events in vivo
17. Joint structural annotation of small molecules using liquid chromatography retention order and tandem mass spectrometry data
18. Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics
19. Serum metabolic traits reveal therapeutic toxicities and responses of neoadjuvant chemoradiotherapy in patients with rectal cancer.
20. Targeting Xkr8 via nanoparticle-mediated in situ co-delivery of siRNA and chemotherapy drugs for cancer immunochemotherapy
21. Sequence-specific viral RNA capture and concentration by type III CRISPR system enhance diagnostic.
22. Compact Cas9d and HEARO enzymes for genome editing discovered from uncultivated microbes
23. Biomimetic electrodynamic nanoparticles comprising ginger-derived extracellular vesicles for synergistic anti-infective therapy
24. Ligand-switchable nanoparticles resembling viral surface for sequential drug delivery and improved oral insulin therapy
25. Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag
26. Nano3P-seq: transcriptome-wide analysis of gene expression and tail dynamics using end-capture nanopore cDNA sequencing
27. Native mass spectrometry combined with enzymatic dissection unravels glycoform heterogeneity of biopharmaceuticals.
28. A general method for chemogenetic control of peptide function
29. Functionalizing DNA origami to investigate and interact with biological systems
30. Natural variations of SLG1 confer high-temperature tolerance in Indian rice.
31. Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells
32. Natural variation of an EF-hand Ca2+-binding-protein coding gene confers saline-alkaline tolerance in maize.
33. Nature-inspired design of motif-specific antibody scaffolds
34. Flash drug release from nanoparticles accumulated in the targeted blood vessels facilitates tumour treatment.
35. Direct encapsulation of biomolecules in semi-permeable microcapsules produced with double-emulsions
36. In vivo surface-enhanced Raman scattering nanosensor for the real-time monitoring of multiple stress signalling molecules in plants
37. Natural variation of OsGluA2 is involved in grain protein content regulation in rice.
38. High-throughput robust single-cell DNA methylation profiling with sciMETv2
39. Functionally integrating nanoparticles alleviate deep vein thrombosis in pregnancy and rescue intrauterine growth restriction.
40. Biosynthesis of mushroom-derived type II ganoderic acids by engineered yeast
41. In a CRISPR/Cas9-based mouse model of PRPF31 retinitis pigments, gene augmentation prevents retinal degeneration.
42. Anomalous inapplicability of nacre-like architectures as impact-resistant templates in a wide range of impact velocities
43. Metabolic and proteomic signatures of type 2 diabetes subtypes in an Arab population
44. Study the application of nanocarriers for gene expression in model plants.
45. Maintaining a healthy equilibrium between biotic and abiotic factors using biotechnological tools.
46. Nanozyme-reinforced hydrogel as an H2O2-driven oxygenator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy
47. Studying the procedure of natural decomposition.
48. Comprehensive multi-attribute method workflow for biotherapeutic characterization and current good manufacturing practices testing
49. Incorporating biomimicry for the detection of tumour cells.
50. Purification of thermostable phytase.

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